


Lamivudine and adefovir are no longer recommended due to high incidence of.SNRIs raise levels of serotonin and norepinephrine, two neurotransmitters in the brain that play a key role in stabilizing mood.Examples include duloxetine (Cymbalta), venlafaxine (Effexor) and desvenlafaxine ( Pristiq).Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants.

They are effective in treating depression, and they have fewer side effects than the other antidepressants.SSRIs block the reuptake, or absorption, of serotonin in the brain.

This makes it easier for the brain cells to receive and send messages, resulting in better and more stable moods.They are called “selective” because they mainly seem to affect serotonin, and not the other neurotransmitters.SSRIs and SNRIs may have the following side effects:Examples include citalopram ( Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil) and sertraline (Zoloft).There have been reports that people who use SSRIs and SNRIs, and especially those under the age of 18 years, may experience thoughts of suicide, especially when they first start using the drugs.All antidepressants carry a black-box warning to this effect, as required by the Food and Drug Administration (FDA).Tricyclic antidepressants (TCAs) are so named because there are three rings in the chemical structure of these medications. They are used to treat depression, fibromyalgia, some types of anxiety, and they can help control chronic pain.Tricyclics may have the following side effects:Examples include amitriptyline (Elavil), amoxapine- clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil) and trimipramine (Surmontil).
